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last updated: 27.02.2011

Zum Nachlesen - NOTES, NOS

Overview

Organisations

Technology

This work describes the use of an over-the-scope-clip system (OTSC), made of super-elastic Nitinol and a specially designed tissue-approximating double jaw endoscopic grasper for gastric closure. The OTSC is a clipping system mounted at the tip of the endoscope and is used for the treatment of gastrointestinal bleeding or gastrointestinal organ perforations. An enlarged version of the OTSC is now under investigation for NOTES.
Schurr MO., Arezzo A., Ho CN., Anhoeck G., Buess G., Di Lorenzo N. The OTSC clip for endoscopic organ closure in NOTES: device and technique. Minim Invasive Ther Allied Technol 2008;17:262-6.

Description of the constraints generated by transluminal surgery and the technological pathways.
Swanstrom L.L., Kozarek R., Pasricha P.J., Gross S., Birkett D., Park P.O., Saadat V., Ewers R., Swain P. Development of a new access device for transgastric surgery. J Gastrointest Surg 2005;9:1129-1136.

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Concepts and philosophy

This paper reviews the problems encountered in NOTES and provides possible temporary solutions.
Mintz Y., Horgan S., Cullen J., Stuart D., Falor E., Talamini MA. NOTES: A Review of the Technical Problems Encountered and Their Solutions. J Laparoendosc Adv Surg Tech A August-2008;18:583-7.

This article aims to answer a highly debated question: can gastroenterologists easily learn the procedure-related surgical knowledge or is it is easier to teach surgeons to handle the conventional flexible endoscopes.
Wagner OJ., Hagen M., Morel P., Inan I., Candinas D., Vorburger SA. Who Should Do NOTES? Initial Endoscopic Performance of Laparoscopic Surgeons Compared to Gastroenterologists and Untrained Individuals. J Gastrointest Surg August-2008;23. [Epub ahead of print].

Evaluation of models, techniques, outcomes, pitfalls,and applicability to the clinical setting of natural orifice translumenal endoscopic surgery (NOTES) for performing intra-abdominal surgery through a systematic review of the literature.
Flora ED., Wilson TG., Martin IJ., Oʼrourke NA., Maddern GJ.A Review of Natural Orifice Translumenal Endoscopic Surgery (NOTES) for Intra-abdominal Surgery: Experimental Models, Techniques, and Applicability to the Clinical Setting. Ann Surg April-2008;247(4):583-602.

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Experimental work

Perioperative hematologic parameters during NOTES was compared with those during standard laparoscopy in 12 swines randomized to transgastric peritoneoscopy with air or diagnostic laparoscopy using carbon dioxide.
Bingener J., Michalek J., Van Sickle K., Schwesinger W. Randomized blinded trial shows relative thrombocytopenia in natural orifice translumenal endoscopic surgery compared with standard laparoscopy in a porcine survival model. Surg Endosc September-2008;22:2067-71. Epub 2008 Jul 2.

Serum interleukins and peritoneal cellular response have been utilized to support the immunologic difference between open and laparoscopic surgery. This study explores the difference between cytokine levels during NOTES and laparoscopic peritoneoscopy.
Bingener J., Krishnegowda NK., Michalek JE. Immunologic parameters during NOTES compared with laparoscopy in a randomized blinded porcine trial. Surg Endosc September-2008. [Epub ahead of print].

The aim of this pilot study was to compare adhesion formation after performance and subsequent repair of colonic perforation via transgastric, laparoscopic, or open surgical techniques and to test the feasibility and outcome of transgastric management of bowel perforation in a prepared model.
Pham BV., Morgan K., Romagnuolo J., Glenn J., Bazaz S., Lawrence C et al. Pilot comparison of adhesion formation following colonic perforation and repair in a pig model using a transgastric, laparoscopic, or open surgical technique. Endoscopy August-2008;40:664-9.

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Human Applications

This paper describes an innovative technique in which the entire colon is extracted transvaginally to avoid any abdominal extraction incision in a female patient with hereditary nonpolyposis colon cancer who required total colectomy and hysterectomy.
Dozois EJ., Larson DW., Dowdy SC., Poola VP., Holubar SD., Cima RR. Transvaginal colonic extraction following combined hysterectomy and laparoscopic total colectomy: a natural orifice approach. Tech Coloproctol August-2008. Epub ahead of print.
This paper reports a transumbilical approach for the endoscopic appendectomy in 8 out of 12 patients in which the procedure was attempted.
Palanivelu C., Rajan PS., Rangarajan M., Parthasarathi R., Senthilnathan P., Praveenraj P. Transumbilical Endoscopic Appendectomy in Humans: On the Road to NOTES: A Prospective Study. J Laparoendosc Adv Surg Tech A. August-2008;18:579-82.
Standard management of walled-off pancreatic necrosis (WOPN), a known complication of acute and chronic pancreatitis, is open surgical debridement and drainage, a procedure associated with substantial morbidity and mortality. This study presents a novel minimally invasive approach to adequately remove and drain pancreatic necrosis. In 5 of 6 cases of WOPN treated with minimally invasive laparoendoscopic surgery, conventional surgery was avoided over a median follow-up of 14 months.
Fischer A., Schrag HJ., Keck T., Hopt UT., Utzolino S. Debridement and drainage of walled-off pancreatic necrosis by a novel laparoendoscopic rendezvous maneuver: experience with 6 cases. Gastrointest Endosc May-2008;67(6):871-8. Epub 2008 Mar 26.

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Access/Closure

This video describes a rendez-vous procedure using simultaneous transgastric and transcolonic approaches to perform a small bowel resection. This is done in order to provide greater range of motion and freedom of movement.
Auyang ED., Vaziri K., Volckmann E., Martin JA., Soper NJ., Hungness ES. NOTES: cadaveric rendezvous hybrid small bowel resection. Surg Endosc July-2008. Epub ahead of print.

This article presents a single-port laparoscopic colorectal surgery using a Uni-X [TM] Single Port Access Laparoscopic System with a multi-channel cannula and specially designed curved laparoscopic instrumentation. The abdomen was approached through a 3.5 cm incision via the umbilicus and a single-port access device was utilized to perform a right hemicolectomy on a patient with an unresectable cecal polyp and a body mass index of 35. Ligation of the ileocolic artery was done with a LigaSure device and was followed by colonic mobilization, extraction and extracorporeal ileocolic anastomosis.
Remzi FH., Kirat HT., Kaouk JH., Geisler DP.SINGLE-PORT LAPAROSCOPY IN COLORECTAL SURGERY. Colorectal Dis August-2008. Epub ahead of print.
NOTUS Cholecystectomy: single incision performed through laparoscopic incisions placed within the umbilicus.
Nguyen NT., Reavis KM., Hinojosa MW., Smith BR., Wilson SE. Laparoscopic Transumbilical Cholecystectomy Without Visible Abdominal Scars. J Gastrointest Surg August-2008. Epub ahead of print.


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Reviews